Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Lef1  lymphoid enhancer binding factor 1   (Synonyms: Lef-1, lymphoid enhancer factor 1)
Results	Reference
1	J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17
1	J:314666 Balasubramanian R, Min X, Quinn PMJ, Giudice QL, Tao C, Polanco K, Makrides N, Peregrin J, Bouaziz M, Mao Y, Wang Q, da Costa BL, Buenaventura D, Wang F, Ma L, Tsang SH, Fabre PJ, Zhang X, Phase transition specified by a binary code patterns the vertebrate eye cup. Sci Adv. 2021 Nov 12;7(46):eabj9846
1	J:218165 Bankhead EJ, Colasanto MP, Dyorich KM, Jamrich M, Murtaugh LC, Fuhrmann S, Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis. Am J Pathol. 2015 Jan;185(1):197-213
1	J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58
1	J:229892 Bosada FM, Devasthali V, Jones KA, Stankunas K, Wnt/beta-catenin signaling enables developmental transitions during valvulogenesis. Development. 2016 Mar 15;143(6):1041-54
1	J:313961 Caramello A, Galichet C, Rizzoti K, Lovell-Badge R, Dentate gyrus development requires a cortical hem-derived astrocytic scaffold. Elife. 2021 Jan 4;10:e63904
1	J:331511 Caramello A, Galichet C, Sopena ML, Lovell-Badge R, Rizzoti K, The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX. Dev Neurobiol. 2022 Oct;82(7-8):565-580
1	J:227707 Carroll LS, Capecchi MR, Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/beta-catenin signaling. Development. 2015 Dec 1;142(23):4056-67
1	J:336856 Chen X, Li N, Hu P, Li L, Li D, Liu H, Zhu L, Xiao J, Liu C, Deficiency of Fam20b-Catalyzed Glycosaminoglycan Chain Synthesis in Neural Crest Leads to Cleft Palate. Int J Mol Sci. 2023 Jun 1;24(11)
1	J:201586 Das A, Tanigawa S, Karner CM, Xin M, Lum L, Chen C, Olson EN, Perantoni AO, Carroll TJ, Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation. Nat Cell Biol. 2013 Sep;15(9):1035-44
1	J:340939 Deacon E, Li A, Boivin F, Dvorkin-Gheva A, Cunanan J, Bridgewater D, beta-Catenin in the kidney stroma modulates pathways and genes to regulate kidney development. Dev Dyn. 2023 Sep;252(9):1224-1239
1	J:252728 Elo T, Lindfors PH, Lan Q, Voutilainen M, Trela E, Ohlsson C, Huh SH, Ornitz DM, Poutanen M, Howard BA, Mikkola ML, Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty. Sci Rep. 2017 Jul 11;7(1):5049
1	J:317071 Ferguson J, Devarajan M, DiNuoscio G, Saiakhova A, Liu CF, Lefebvre V, Scacheri PC, Atit RP, PRC2 Is Dispensable in Vivo for beta-Catenin-Mediated Repression of Chondrogenesis in the Mouse Embryonic Cranial Mesenchyme. G3 (Bethesda). 2018 Feb 2;8(2):491-503
1	J:213513 Gao Y, Toska E, Denmon D, Roberts SG, Medler KF, WT1 regulates the development of the posterior taste field. Development. 2014 Jun;141(11):2271-8
1	J:229313 Goodnough LH, Dinuoscio GJ, Atit RP, Twist1 contributes to cranial bone initiation and dermal condensation by maintaining wnt signaling responsiveness. Dev Dyn. 2016 Feb;245(2):144-56
1	J:226667 Goodnough LH, Dinuoscio GJ, Ferguson JW, Williams T, Lang RA, Atit RP, Distinct requirements for cranial ectoderm and mesenchyme-derived wnts in specification and differentiation of osteoblast and dermal progenitors. PLoS Genet. 2014 Feb;10(2):e1004152
1	J:311537 Guo L, Beck T, Fulmer D, Ramos-Ortiz S, Glover J, Wang C, Moore K, Gensemer C, Morningstar J, Moore R, Schott JJ, Le Tourneau T, Koren N, Norris RA, DZIP1 regulates mammalian cardiac valve development through a Cby1-beta-catenin mechanism. Dev Dyn. 2021 Oct;250(10):1432-1449
1*	J:207609 Hilliard SA, Yao X, El-Dahr SS, Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014 Mar 1;387(1):1-14
1	J:189075 Hiremath M, Dann P, Fischer J, Butterworth D, Boras-Granic K, Hens J, Van Houten J, Shi W, Wysolmerski J, Parathyroid hormone-related protein activates Wnt signaling to specify the embryonic mammary mesenchyme. Development. 2012 Nov;139(22):4239-49
1*	J:191972 Huang S, Zhu X, Liu Y, Tao Y, Feng G, He L, Guo X, Ma G, Wls is expressed in the epidermis and regulates embryonic hair follicle induction in mice. PLoS One. 2012;7(9):e45904
1	J:333402 Ihermann-Hella A, Hirashima T, Kupari J, Kurtzeborn K, Li H, Kwon HN, Cebrian C, Soofi A, Dapkunas A, Miinalainen I, Dressler GR, Matsuda M, Kuure S, Dynamic MAPK/ERK Activity Sustains Nephron Progenitors through Niche Regulation and Primes Precursors for Differentiation. Stem Cell Reports. 2018 Oct 9;11(4):912-928
1	J:119729 Iwatsuki K, Liu HX, Gronder A, Singer MA, Lane TF, Grosschedl R, Mistretta CM, Margolskee RF, Wnt signaling interacts with Shh to regulate taste papilla development. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2253-8
1*	J:308476 Le Rolle M, Massa F, Siggers P, Turchi L, Loubat A, Koo BK, Clevers H, Greenfield A, Schedl A, Chaboissier MC, Chassot AA, Arrest of WNT/beta-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries. Proc Natl Acad Sci U S A. 2021 Jul 27;118(30):e2023376118
1	J:237533 Lian G, Dettenhofer M, Lu J, Downing M, Chenn A, Wong T, Sheen V, Filamin A- and formin 2-dependent endocytosis regulates proliferation via the canonical Wnt pathway. Development. 2016 Dec 01;143(23):4509-4520
1	J:183911 Narhi K, Tummers M, Ahtiainen L, Itoh N, Thesleff I, Mikkola ML, Sostdc1 defines the size and number of skin appendage placodes. Dev Biol. 2012 Apr 15;364(2):149-61
1	J:330186 Nguyen H, Sokpor G, Parichha A, Pham L, Saikhedkar N, Xie Y, Ulmke PA, Rosenbusch J, Pirouz M, Behr R, Stoykova A, Brand-Saberi B, Nguyen HP, Staiger JF, Tole S, Tuoc T, BAF (mSWI/SNF) complex regulates mediolateral cortical patterning in the developing forebrain. Front Cell Dev Biol. 2022;10:1011109
1	J:257052 Roker LA, Nemri K, Yu J, Wnt7b Signaling from the Ureteric Bud Epithelium Regulates Medullary Capillary Development. J Am Soc Nephrol. 2017 Jan;28(1):250-259
1	J:269436 Sabbagh MF, Heng JS, Luo C, Castanon RG, Nery JR, Rattner A, Goff LA, Ecker JR, Nathans J, Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells. Elife. 2018 Sep 6;7:e36187
1	J:345231 Satta JP, Lan Q, Taketo MM, Mikkola ML, Stabilization of Epithelial beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis. J Invest Dermatol. 2023 Dec 28;
1*	J:18378 van Genderen C, Okamura RM, Farinas I, Quo RG, Parslow TG, Bruhn L, Grosschedl R, Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev. 1994 Nov 15;8(22):2691-703
1	J:137691 Yin Y, White AC, Huh SH, Hilton MJ, Kanazawa H, Long F, Ornitz DM, An FGF-WNT gene regulatory network controls lung mesenchyme development. Dev Biol. 2008 Jul 15;319(2):426-36
1*	J:248919 Yu W, Li X, Eliason S, Romero-Bustillos M, Ries RJ, Cao H, Amendt BA, Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation. Dev Biol. 2017 Sep 1;429(1):44-55